Name | sodium hydrogen L-aspartate |
Synonyms | Ccris 7917 L-Sodium aspartic SodiumL-Aspartate Sodium L-Aspartate Monosodium aspartate aspartatemonosodiumsalt Disodium 2-aminosuccinate sodium hydrogen L-aspartate Aspartic acid disodium salt disodium 2-aminobutanedioate L-Aspartic acid 4-sodium salt sodium (2S)-2-aminobutanedioate MONOSODIUM L-ASPARTATE DIHYDRATE L-Aspartic acid hydrogen 4-sodium salt Sodium (2S)-2-amino-3-carboxypropanoate sodium 3-amino-4-hydroxy-4-oxobutanoate |
CAS | 3792-50-5 |
EINECS | 223-264-0 |
InChI | InChI=1/C4H7NO4.Na/c5-2(4(8)9)1-3(6)7;/h2H,1,5H2,(H,6,7)(H,8,9);/q;+1/p-2/t2-;/m0./s1 |
Molecular Formula | C4H5NNa2O4 |
Molar Mass | 177.07 |
Density | 1.665[at 20℃] |
Melting Point | ~140°C (dec.) |
Specific Rotation(α) | [α]D20 +18.0~+22.0° (c=2, dil. HCl) |
Water Solubility | 631.7g/L at 20℃ |
Solubility | H2O: ≥100mg/mL |
Vapor Presure | 0Pa at 20℃ |
Storage Condition | Inert atmosphere,Room Temperature |
MDL | MFCD00152960 |
Physical and Chemical Properties | Colorless to white columnar crystals, or white crystalline powder. The taste was mild, with taste threshold of 0.16%. Melting point 140.4 °c. Soluble in water (66.7%,20 C), insoluble in ethanol. Natural products are present in sugar beet, milk protein, etc. |
Use | L-aspartic acid sodium has excellent fresh, antiseptic effect, widely used in food industry fresh agent, preservative, can replace monosodium glutamate. In the pharmaceutical industry, it can be used as the main raw material of heart disease drugs, liver function promoter, ammonia antidote, fatigue remover and amino acid infusion. It is also widely used in industry. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 3 |
Reference Show more | 1. [IF=4.539] Qing Wang et al."Synthesis and properties of pH-dependent N-acylglutamate/aspartate surfactants."Colloid Surface A. 2022 May;640:128474 |
LogP | -4.25 at 20℃ |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
introduction | l-aspartate sodium, also known as amino-l-succinate monosodium; L-aspartate sodium (1 water), etc., English name: Sodium L-aspartate, for amino acids and derivatives; Amino acid salt; Food and feed additives are colorless to white columnar crystals, or white crystalline powder. The taste is light and the taste threshold is 0.16%. Melting point 140.4 ℃. Soluble in water (66.7%,20 ℃), insoluble in ethanol. Natural products exist in sugar beets, milk protein, etc. |
application | L-aspartic acid, as a bulk amino acid product, has a wide range of uses in medicine, food and chemical industry. In terms of medicine, it is mainly used as the main component for the treatment of heart disease, liver function promoters, ammonia antidotes, fatigue eliminators and amino acid infusions. It is also L aspartate (potassium, magnesium, calcium and sodium), alanine and asparagine The synthetic raw material of a variety of small molecule drugs; in the food industry, L-aspartic acid is a good nutritional supplement, added to various refreshing beverages, and is the main raw material for the production of sugar substitute aspartame; in the chemical industry, it can be used as a raw material for the manufacture of synthetic resins and is widely used in the synthesis of environmentally friendly materials polyaspartic acid. L-aspartate sodium is a kind of amino acid sodium salt, widely used in food industry preservatives, preservatives, can replace monosodium glutamate; pharmaceutical industry as an intermediate. |
identification test | take 5ml of 0.1% sample aqueous solution, add lml of indantrione test solution (TS-250), and turn purple after heating for 3min. Positive for sodium salt reaction (IT-28). |
content analysis | accurately weigh 0.1g of the sample pre-dried for 5 hours in a dryer containing silica gel, dissolve in 0.5ml of water, immediately add 3ml of formic acid and 100ml of glacial acetic acid, add 0.5ml of α-naphthol benzene solution (TS-153), and titrate with 0.1mol/L perchloric acid solution to the green end point. The same blank test was conducted. 0.1mol/L perchloric acid solution per Ml is equivalent to 8.655mg of sodium L-aspartate (C4H6NNaO4?H2O). |
toxicity | GRAS(FEMA). |
usage limit | Japan (1998): beverage 0.1% ~ 0.5%; Sweetener 5.0% ~ 15.0%; Fish cake 0.1% ~ 0.5%; Red sausage 0.1% ~ 0.3%; Gravy soup 0.5% ~ 1.0%; Curry cheese flour paste 0.3% ~ 0.5%, soy sauce 0.1% ~ 0.4%, vinegar 0.5% ~ 1.0%; Spicy laver seasoning liquid 1.0% ~ 2.0%; Canned fish 0.1% ~ 0.5%. |
use | seasoning. It is often used in combination with natural condiments, sodium glutamate, glycine or sodium citrate, sodium succinate, etc. Mainly used in all kinds of curry, vinegar, canned fish, canned vegetables, bread, biscuits, beverages, etc. as flavor improvers. For example, it is used in cool drinks such as orange juice, because of its unique refreshing flavor. It can increase coolness and is often used with polyphosphate. Combined with other condiments, there is a synergistic effect. Combined with sodium saccharin, it has the effect of reducing the bitter taste. Nutritional enhancers. Although it is a non-essential amino acid, it participates in the metabolic process and plays an important role in physiology. Unlimited usage. Most of them are used as food additives. This product has a similar taste of L-glutamic acid, and it is used with nucleic acid series condiments, and its fragrance is doubled. When used as a condiment, it is generally used with natural condiments, sodium glutamate, glycine, etc., some with sodium citrate, sodium succinate and other organic acids, and some are used together with polymeric phosphate in refreshing beverages. This product is mainly used for aquatic products, noodles in soup and other foods. The characteristics of sodium aspartate are:(1) when added to cool drinks such as orange juice, it can increase the coolness due to its unique refreshing flavor;(2) when combined with other condiments, it can increase the efficiency to make a strong fragrance;(3) when combined with sodium saccharin, it can remove bitter taste;(4) when added to soda, Coca Cola and other carbonated drinks, it can increase the retention of carbon dioxide;(5) Adding to aquatic products can make the fragrance stronger. In addition, it has the function of inhibiting changes in food color and aroma. L-aspartate sodium has excellent fresh and antiseptic effects, and is widely used in the food industry as a fresh agent and preservative, which can replace monosodium glutamate. In the pharmaceutical industry, it can be used as the main raw material for heart disease drugs, liver function promoters, ammonia antidote, fatigue eliminator and amino acid infusion. It is also widely used in industry. |
Production method | It is obtained by neutralizing L-aspartic acid with sodium hydroxide. L-aspartic acid is obtained by fermentation of bacteria (Escherichia coli, etc.), and it is obtained by adding sodium hydroxide to neutralize and crystallize. |